European Molecular
Biology Computing Network - Biocomputing Tutorials CRI-MAP"

CRI-MAP - Introduction

CRI-MAP tutorial contents:

Manuals Manual Table of Contents Data Sets Data Formatting Mapping & LOD scores Testing & X-overs Bibliography & Links
Web & text
Web Manual
Table of
data with
Testing &
Other Links

CRI-MAP is a programme for the construction of genetic maps from gene linkage data. From the CRI-MAP Manual introduction by its author, Dr. Phil Green ...

"The main purpose of CRI-MAP is to allow rapid, largely automated
construction of multilocus linkage maps (and to facilitate the attendant
tasks of assessing support relative to alternative locus orders,
generating LOD tables, and detecting data errors). Although originally
designed to handle codominant loci (e.g. RFLPs) scored on pedigrees
"without missing individuals", such as CEPH or nuclear families, it can
now (with some caveats described below) be used on general pedigrees,
and some disease loci."

In addition to its primary mapping function, CRI-MAP can also estimate recombination fractions & LOD scores between pairs of loci, perform multipoint likelihood calculations, and point out recombinant chromosomes in pedigrees.

This tutorial is divided into three parts:

  1. Data Formatting data input & formatting
  2. Analysis 1 mapping & LOD scores
  3. Analysis 2 map testing & X-overs

Throughout, you will find links to:

For those of you without data, please get some from the

This is an INTERACTIVE tutorial; you will benefit most by FOLLOWING the instructions, through READING the examples, and DOING the exercises! Exercises are indicated by italics in nested paragraphs ...

For the majority of the exercises, you need to run an interactive login session with your EMBnet Node host computer while you read the tutorial with your web browser. Be certain your web browser is set-up to call a terminal emulation programme or xterm window in response to the telnet:// URL. If you need some help with these technical details, browse the HELP! page.

Please choose your EMBnet Node host from this list, and use the link back to the CRI-MAP tutorial to continue.
Follow your usual login procedure on the telnet window that will appear. Move this window to the right of your screen, so it "fits" between the up and down scroll bar arrows of your web browser, like this.

Now you are ready for
Part 1 - data input & formatting   Data Formatting

Good luck, Bonne chance, Held og lykke, viel Glück, Succes, ...;

Have some fun doing this tutorial, and PLEASE send your comments and questions!

If you are keen to have MORE information about CRI-MAP, check the Bibliography Page.  

Oh, and if this information came to you V E R Y   S L O W L Y, check the PING! page to find which of the EMBnet Web Server Nodes is "closest" to you!

SRS, Blast, Fasta Linkage ACeDB GDB v6 EMBnet Biocomputing Tutorials Internet for Biologists CRI-MAP DNA Sequence Analysis On-line Mendelian  
Inheritance in Man


Comments? Questions? Accolades? Comments? Questions? Accolades?
Please send them to David Featherston Please   ( )
Updated on Wednesday, 20 November, 1996
Copyright © 1995-1996 by David W. Featherston