64 loci
CHROMOSOME # | |||||||||
---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | |
12 | 13 | 14 | 15 | 16 | 17 | 18 | X | Y |
CHROMOSOME #1: 5 loci. | ||
---|---|---|
Location | Symbol | Name |
1p25-p24 | ESR | estrogen receptor |
1q15-q16 | CGA | pituitary glycoprotein hormone, alpha polypeptide |
1q25 | IFNA | interferon, alpha, leukocyte |
1q25-q26 | IFNB1 | interferon, beta 1 |
1q28-q29 | RLN | relaxin |
CHROMOSOME #2: 4 loci. | ||
---|---|---|
Location | Symbol | Name |
2p16-p12 | FSHB | follitropin, beta polypeptide |
2q11-q21 | INSR | insulin receptor |
2q12-q13 | LCIP | Leydig cell insulin-like protein |
2 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
CHROMOSOME #3: 7 loci. | ||
---|---|---|
Location | Symbol | Name |
3p13-p11 | PRM1 | protamine 1 |
3p12-p11 | TNP2 | transition protein 2 |
3q11-q13 | IL1A | interleukin 1 alpha |
3q11-q14 | IL1B | interleukin 1 beta |
3q22-q23 | FSHR | follitropin receptor |
3q22-q23 | LHCGR | lutropin/choriogonadotropin receptor |
3 | PRM2 | protamine 2 |
CHROMOSOME #4: 5 loci. | ||
---|---|---|
Location | Symbol | Name |
4q15-q24 | NGFB | nerve growth factor, beta polypeptide |
4 | AFD | abdominal fat deposition |
4 | HSP | heat shock protein |
4 | TGR | total growth rate (birth to 70 kg) |
4 | TSHB | thyrotropin (thyroid stimulating hormone), beta polypeptide |
CHROMOSOME #5: 3 loci. | ||
---|---|---|
Location | Symbol | Name |
5p15 | ACR | prepro-acrosin |
5p12-q11 | IFNG | interferon, gamma |
5q23-q24 | IGF1 | insulin-like growth factor 1 |
CHROMOSOME #6: 7 loci. | ||
---|---|---|
Location | Symbol | Name |
6cen-q12 | LIPE | lipase, hormone sensitive |
6cen-q21 | TGFB1 | transforming growth factor, beta 1 |
6q11-q12 | CRC (HAL, RYR1) | calcium release channel (ryanodine receptor; halothane sensitivity; malignant hyperthermia) |
6q21 | LHB | lutropin, beta polypeptide |
6q31-q33 | PRKACB | protein kinase, cAMP-dependent catalytic, beta 1 |
6 | BNP1 | brain natriuretic peptide |
6 | OTF2 | octamer binding transcription factor 2 |
CHROMOSOME #7: 5 loci. | ||
---|---|---|
Location | Symbol | Name |
7p11 | HSPA1 | heatshock protein 70 kDa protein 1 |
7p11-q11 | TNFA | tumor necrosis factor, alpha |
7p11-q11 | TNFB | tumor necrosis factor, beta |
7 | CYP21 | cytochrome P450, subfamily XXI (steroid 21-hydroxylase) |
7 | PRL | prolactin |
CHROMOSOME #8: 4 loci. | ||
---|---|---|
Location | Symbol | Name |
8cen-q12 | PDGFRA | platelet-derived growth factor receptor, alpha |
8q12 | ALB | albumin |
8q12-qter | IL2 | interleukin 2 |
8 | I | dominant white (inhibition of color; patch; roan) |
CHROMOSOME #9: 1 locus. | ||
---|---|---|
Location | Symbol | Name |
9 | OTF11 | octamer binding transcription factor 11 |
CHROMOSOME #12: 6 loci. | ||
---|---|---|
Location | Symbol | Name |
12p14 | GH | somatotropin |
12p14 | PRKAR1A | protein kinase, cAMP-dependent regulatory type I alpha |
12q12-q14 | TP53 | tumour protein p53 |
12q | INHBA | inhibin beta A |
12 | ALOX12 | arachidonate 12-lipoxygenase |
12 | INHBB | inhibin beta |
CHROMOSOME #13: 3 loci. | ||
---|---|---|
Location | Symbol | Name |
13q31 | TF | transferrin |
13 | IGR | initial growth rate (birth to 30 kg) |
13 | PIT1 | pituitary-specific transcription factor (growth hormone factor 1) |
CHROMOSOME #14: 3 loci. | ||
---|---|---|
Location | Symbol | Name |
14q22-q23 | RYR2 | ryanodine receptor, cardiac muscle |
14q24-q25 | HSPA6 | heatshock protein 70 kDa protein 6 |
14q24-q26 | PLAU | plasminogen activator, urokinase |
CHROMOSOME #15: 2 loci. | ||
---|---|---|
Location | Symbol | Name |
15p12-p13 | LCT | lactase |
15q24-q25 | TNP1 | transition protein 1 |
CHROMOSOME #16: 2 loci. | ||
---|---|---|
Location | Symbol | Name |
16q13-q14 | FSA | follistatin |
16q13-q14 | GHR | somatotropin receptor |
CHROMOSOME #17: 1 locus. | ||
---|---|---|
Location | Symbol | Name |
17 | ENDO | dynorphin |
CHROMOSOME #18: 3 loci. | ||
---|---|---|
Location | Symbol | Name |
18q24 | IGFBP3 | insulin-like growth factor binding protein 3 |
18q24 | INHBA | inhibin beta A |
18q | CFTR | cystic fibrosis transmembrane conductance regulator |
CHROMOSOME X: 1 locus. | ||
---|---|---|
Location | Symbol | Name |
X | ZFX | zinc finger protein, X-linked |
CHROMOSOME Y: 2 loci. | ||
---|---|---|
Location | Symbol | Name |
Yp13-p12 | SRY | sex determining region Y |
Y | ZFY | zinc finger protein, Y-linked |
REFERENCES
GeneralArchibald AL, Haley CS, Brown JF, Couperwhite S, McQueen HA, Nocholson D, Coppieters W, Van de Weghe A, Stratil A, Wintero AK, Fredholm M, Larsen NJ, Nielsen VH, Milan D, Woloszyn N, Robic A, Dalens M, Riquet J, Gellin J, Caritez J-C, Burggaud G, Ollivier L, Bidanel J-P, Vaiman M, Renard C, Geldermann H, Davoli R, Ruyter D, Verstege EJM, Groenen MAM, Davies W, Hoyheim B, Keiserud A, Andersson L, Ellegren H, Johansson M, Marklund L, Miller JR, Dear DVA, Signer E, Jeffreys AJ, Moran C, Le Tissier P, Muladno, Rothschild MF, Tuggle CK, Vaske D, Helm J, Liu H-C, Rahman A, Yu T-P, Larson RG, Schmitz CB. The PigMap consortium linkage map of the pig (Sus scrofa). Mammal Genome 1995;6:157-75.
Andersson L, Archibald AL, Gellin, Schook LB. 1st pig gene mapping workshop (PGM1), 7 august 1992, Interlaken, Switzerland. Anim Genet 1993;24:205-16.
Echard G, Milan D, Yerle, Lahbib-Mansais Y, Gellin J. The gene map of the pig (Sus scrofa domestica L.): a review. Cytogenet Cell Genet 1992;61:146-51.
Ellegren H, Chowdhary BP, Johansson M, Fredholm M, Gustavsson, Andersson L. A primary linkage map of the porcine genome reveals a low rate of genetic recombination. Genetics 1994;137:1089-100.
Johansson M, Ellegren H, Andersson L. Comparative mapping reveals extensive linkage conservation-but with gene order rearrangements-between the pig and the human genomes. Genomics 1995;25:682-90.
Yerle M, Lahbib-Mansais Y, Mellink C, Goureau A, Pinton P, Echard G, Gellin J, Zijlstra C, De Haan N, Bosma AA, Chowdhary B, Gu F, Gustavsson I, Thomsen PD, Christensen K, Rettenberger G, Hameister H, Schmitz A, Chaput B, Frelat G. Mammal Genome 1995;6:176-86.
Chromosome #1
Ellegren H. Abundant (A)n-(T)n mononucleotide repeats in the pig genome: linkage mapping of the porcine APOB, FSA, ALOX12, PEPN and RLN loci. Anim Genet 1993;24:367-72.
Ellegren H, Chowdhary BP, Fredholm M, Hoyheim B, Johansson M, Braeuner Nielsen P, Thomsen PD, Andersson L. Aphysically anchored linkage map of pig chromosome 1 uncovers sex- and position-specific recombination rates. Genomics 1994;24:342-50.
Sarmiento UM, Sarmiento JI, Lunney JK, Rishi SS, Mapping of the porcine alpha interferon (IFNA) gene to chromosome #1 by fluoresecence in situ hybridization. Mammal Genome 1993;4:62-3.
Troyer DL, Xie H, Goad DW, Skinner DZ. Use of a new technique to map the porcine alpha interferon gene to chromosome 1. Mammal Genome 1994;5:112-4.
Yerle M, Gellin J, Echard G, Lefevre F, Gillois M. Chromosomal localization of leukocyte interferon gene in the pig (Sus scrofa domestica) by in situ hybridization. Cytogenet Cell Genet 1986;42:129-32.
Chromosome #2
Gu F, Harbitz I, Chowdhary BP, Bosnes M, Gustavsson I. Chromosomal localization of the hormone sensitive lipase (LIPE) and insulin receptor (INSR) genes in pigs. Hereditas 1992;117:231-6.
Rettenberger G, Burkhardt E, Adham IM, Engel W, Fries R, Klett C, Hameister H. Assignment of the Leidig insulin-like hormone to porcine chromosome 2q12-q13 by somatic cell hybrid analysis and fluorescence in situ hybridization. Mammal Genome 1994;5:307-9.
Rohre GA, Alexander LJ, Beattie CW. Mapping the beta subunit of follicle stimulating hormone (FSHB) in the porcine genome. Mammal Genome 1994;5:315-7.
Chromosome #3
Gu F, Chowdhary BP, Johansson M, Andersson L, Gustavsson I. Localization of the IGHG, PRKACB, and TNP2 genes in pigs by in situ hybridization. Mammal Genome 1994;5:195-8.
Johansson M, Ellegren H, Marklund L, Coppieters W, Andersson L. Linkage maps of porcine chromosomes 3, 6, and 9 based on 31 polymorphic markers. Mammal Genome 1994;5:785-90.
Mellink C, Lahbib-Mansais Y, Yerle M, Gellin J. Mapping of the regulatory type I alpha and catalytic beta subunits of cAMP-dependent protein kinase and interleukin 1 alpha and 1 beta in the pig. Mammal Genome 1994;5:298-302.
Rettenberger G, Fries, R. Engel, Scheit KH, Dolf G, Hameister H. Establishement of a partially informative porcine somatic cell hybrid panel and assignment of the loci for transition protein 2 (TNP2) and protamine 1 (PRM1) to chromosome 3 and polyubiquitin (UBC) to chromosome 14. Genomics 1994;21:558-66.
Chromosome #4
Andersson L, Haley CS, Ellegren H, Knott SA, Johansson M, Andersson K, Andersson-Eklund L, Edfors-Lija I, Fredholm M, Hansson I, Haekansson J, Lundstroem K. Genetic mapping of quantitative loci for growth and fatness in pigs. Science 1994;263:1771-4.
Chromosome #5
Rettenberger G, Adham IM, Engel W, Klett C, Hameister H. Assignment of the porcine acrosin gene, ACR, to chromosome 5p15 by fluorescence in situ hybridization (FISH). Mammal Genome 1995;6:60-1.
Winteroe AK, Fredholm M, Andersson L. Assignment of the gene for porcine insulin-like growth factor 1 (IGF1) to chromosome 5 by linkage mapping. Anim Genet 1994;25:37-9.
Chromosome #6
Gu F, Chowdhary BP, Johansson M, Andersson L, Gustavsson I. Localization o fthe IGHG, PRKACB, and TNP2 genes in pigs by in situ hybridization. Mammal Genome 1994;5:195-8.
Johansson M, Ellegren H, Marklund L, Coppieters W, Andersson L. Linkage maps of porcine chromosomes 3, 6, and 9 based on 31 polymorphic markers. Mammal Genome 1994;5:785-90.
Mellink C, Lahbib-Mansais Y, Yerle M, Gellin J. Mapping of the regulatory type I alpha and catalytic beta subunits of cAMP-dependent protein kinase and interleukin 1 alpha and 1 beta in the pig. Mammal Genome 1994;5:298-302.
Chromosome #7
Solinas S, Pauli U, Kuhnert P, Peterhans E, Fries R. Assignment of the porcine tumour necrosis factor alpha and beta genes to the chromosome region 7p11-q11 by in situ hybridization. Anim Genet 1992;23:267-71.
Chromosome #8
Johansson M, Ellegren H, Marklund L, Gustavsson U, Ringmar-Cederberg E, Andersson K, Edfors-Lilja I, Andersson L. The gene for Dominant White color in the pig is closely linked to ALB and PDGFRA on chromosome 8. Genomics 1992;14: 965-969.
Chromosome #12
Ellegren H. Abundant (A)n-(T)n mononucleotide repeats in the pig genome: linkage mapping of the porcine APOB, FSA, ALOX12, PEPN and RLN loci. Anim Genet 1993;24:367-72.
Mellink C, Lahbib-Mansais Y, Yerle M, Gellin J. Mapping of the regulatory type I alpha and catalytic beta subunits of cAMP-dependent protein kinase and interleukin 1 alpha and 1 beta in the pig. Mammal Genome 1994;5:298-302.
Rettenberger G, Klett C, Hameister H. Localization of tumor protein, TP53, on porcine chromosome 12q12-q14. Anim Genet 1993;24:307-9.
Thomsen PD, Fredholm M, Christensen K, Schwerin M. Assignment of the porcine growth hormone gene to chromosome 12. Cytogenet Cell Genet 1990;54:92-4.
Yerle M, Lahbib-Mansais Y, Thomsen PD, Gellin J. Localization of the porcine growth hormone gene to chromosome 12p12-p15. Anim Genet 1993;24:129-31.
Chromosome #13
Andersson L, Haley CS, Ellegren H, Knott SA, Johansson M, Andersson K, Andersson-Eklund L, Edfors-Lija I, Fredholm M, Hansson I, Haekansson J, Lundstroem K. Genetic mapping of quantitative loci for growth and fatness in pigs. Science 1994;263:1771-4.
Chromosome #14
Leeb T, Rettenberger G, Hameister H, Brem G, Brenig B. Construction of a porcine YAC library and mapping of the cardiac muscle ryanodine receptor gene to chromosome 14q22-q23. Mammal Genome 1995;6:37-41.
Chromosome #15
Rettenberger G, Adham IM, Engel W, Klett C, Hameister H. Assignment of the porcine transition protein TNP1 to chromosome 15q24-q25 by fluorescence in situ hybridization (FISH). Mammal Genome 1994;5:249-50.
Chromosome #16
Chowdhary BP, Ellegren H, Johansson M, Andersson L, Gustavsson I. In situ hybridization mapping of the growth hormone receptor (GHR) gene assigns a linkage group (C9, FSA, GHR, and S0105) to chromosome 16 in pigs. Mammal Genome 1994;5:160-2.
Ellegren H. Abundant (A)n-(T)n mononucleotide repeats in the pig genome: linkage mapping of the porcine APOB, FSA, ALOX12, PEPN and RLN loci. Anim Genet 1993;24:367-72.
Chromosome #18
Lahbib-Mansais Y, Yerle M, Pinton P, Gellin J. Chromosomal localization of homeobox genes and associated markers on porcine chromosomes 3, 5, 12, 15, 16 and 18: comparative mapping study with human and mouse. Mammal Genome 1996;7:174-9.
Chromosome Y
Yang H, Fries R, Strnazinger G. The sex-determining region Y (SRY) gene is mapped to p12-p13 of the Y chromosome in pig (Sus scrofa domestica) by in situ hybridization. Anim Genet 1993;24:297-300.
Armando G. Amador © A. G. Amador & R. King
Last update: Saturday, 27 December, 1997 20:30:03
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